Research Laboratories

The Division of Radiological Sciences has 14 research laboratories, comprising 3,225 square feet. The laboratories are equipped for radioactive and non-radioactive radiopharmaceutical synthesis, including:

• a cell culture suite
• a perfusion laboratory
• 6 HPLC and 2 FPLC systems
• 1 UV visible spectrophotometer
• 1 IR detector
• 4 centrifuges
• 5 radioactivity dose calibrators
• 1 electrophoretic power supply and chambers
• 2 TLC radioactivity scanners
• a Packard InstantImager
• a Canberra 1510 Ge detector
• a Waters LC Mass Spectrometer
• 2 Beckman 8000 gamma counters
• a Beckman LS1801 beta counter

Small Animal Imaging Facility

The small animal imaging facility at Washington University is built around State-of-the-Art small animal imaging technology. This technology is housed in newly refurbished laboratory space specifically designed for the non-invasive delineation of disease in rodent models. Additional facilities for support include animal housing, physiologic support and monitoring equipment, surgical procedure rooms, wet-chemistry laboratories and data analysis and archival systems. The Facility is supported by a team of highly trained technologists and includes:

• a microPET-R4 (Concorde MicroSystem Inc., Knoxville, TN)
• 2 microPET-FOCUS - F120 and F220 (Concorde MicroSystem Inc., Knoxville, TN)
• 2 Varian NMR Systems (Palo Alto, Ca) UNITY-INOVA 4.7 tesla MRI/MRS small animal research scanners
• a MicroCAT II System (ImTek Inc., Knoxville, Tennessee)

PET Imaging Facility

The PET imaging devices in our facilities include:

• 2 Siemens ECAT HR⁺962 PET scanner
• a Siemens Biograph PET/CT-2
• a Siemens Biograph TruePoint/TrueView-40

Cyclotron Facility

Radiopharmaceuticals for PET studies are produced in the Washington University Medical Center Cyclotron Facilities. This facility contains:

• 3 cyclotrons
• a Japan Steel Works 16/8
• a Cyclotron Corporation CS-15
• a CTI RDS111 cyclotron
• 14 shielded hot cells
• a laminar flow hot cell
• a general chemistry hot cell with manipulator arms
• 2 gas chromatographs
• 5 HPLC systems
• other equipment necessary for the production of PET radiopharmaceuticals