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DOE Metals - Publication List
| Articles | Abstracts |
 
Articles
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  • Fujibayashi Y, Cutler CS, Anderson CJ, McCarthy DW, Jones LA, Sharp T, Yonekura, Welch MJ. Comparative Studies of Cu-64-ATSM and C-11-Acetate in an Acute Myocardial Infarction Model: Ex Vivo Imaging of Hypoxia in Rats. Nucl. Med. Biol. 26:117-121, 1999.
  • Cutler CS, Giron MC, Reichert DE, Snyder AZ, Herrero P, Anderson CJ, Quarless DA, Koch SA and Welch MJ. Evaluation of Gallium-68 Tris(2-Mercaptobenzyl)Amine: A Complex with Brain and Myocardial Uptake. Nucl. Med. Biol. 26:305-316, 1999.
  • McCarthy DW, Bass LA, Cutler PD, Shefer RE, Klinkowstein RE, Herrero P, Lewis JS, Cutler CS, Anderson CJ and Welch MJ. High Purity Production and Potential Applications of Copper-60 and Copper-61. Nucl. Med. Biol. 26:351-358, 1999.
  • Lewis JS, McCarthy DW, McCarthy TJ, Fujibayashi Y and Welch MJ. Evaluation of 64Cu-ATSM In Vitro and In Vivo in a Hypoxic Tumor Model. J. Nucl. Med. 40:177-184, 1999.
  • Reichert DE, Lewis JS, Anderson CJ. Metal Complexes as Diagnostic Tools. Coord. Chem. Rev. 1999; 184:3-66.
  • Cutler CS, Lewis JS, Anderson CJ. Utilization of Metabolic, Transport and Receptor-Mediated Processes to Deliver Agents for Cancer Diagnosis. Adv. Drug Del. Rev. 37:189-212, 1999.
  • Welch MJ, Reichert DE, Anderson CJ and Martell AE. Chemistry of Gallium, Indium and Copper in the Design of New Radiopharmaceuticals. Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine, 5th Ed., M Nicolini and U Mazzi (eds), Servizi Grafici Editoriali, Padova 43-51, 1999.
  • Edwards WB, Anderson CJ, Fields GB and Welch MJ. Evaluation of Collagen-based Peptides as Imaging Agents for α3β1 Integrin. Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine, 5th Ed., M Nicolini and U Mazzi (eds), Servizi Grafici Editoriali, Padova 527-531, 1999.
  • Dearling JLJ, Mullen GED, Lewis JS, Rae MT, Zweit J, Welch MJ and Blower PJ. Hypoxia-Selective Copper-64 Complexes. Technetium, Rhenium and Other Metals in Chemistry and Nuclear Medicine, 5th Ed., M Nicolini and U Mazzi (eds), Servizi Grafici Editoriali, Padova 599-604, 1999.
  • Anderson CJ and Welch MJ. Radiometal-Labeled Agents (Non-Technetium) for Diagnostic Imaging. Chem. Rev. 99:2219-2234, 1999.
  • Welch MJ and McCarthy TJ. The Potential Role of Generator-Produced Radiopharmaceuticals in Clinical PET. J. Nucl Med. 41:315-317, 2000.
  • Bass LA, Wang M, Welch MJ and Anderson CJ. In Vivo Transchelation of Copper-64 from TETA-Octreotide to Superoxide Dismutase in Rat Liver. Bioconjugate Chem. 11:527-532, 2000.
  • Chao KSC, Bosch WR, Mutic S, Lewis JS, Dehdashti F, Mintun MA, Dempsey JF, Perez CA, Purdy JA and Welch MJ. A Novel Approach to Overcome Hypoxic Tumor Resistance: Cu-ATSM-Guided Intensity-Modulated Radiation Therapy. Int. J. Radiat. Oncol. Biol. Phys. 49:1171-1182, 2001.
  • Lewis JS, Laforest R, Buettner TL, Song SK, Fujibayashi Y, Connett JM and Welch MJ. Copper-64-diacetyl-bis(N4-methylthiosemicarbazone): An agent for radiotherapy. Proc. Natl. Acad. Sci. U.S.A. 98:1206-1211, 2001.
  • Lewis JS, Sharp TL, Laforest R, Fujibayashi Y and Welch MJ. Tumor Uptake of Copper-Diacetyl-Bis(N4-Methylthiosemicarbazone): Effect of Changes in Tissue Oxygenation. J. Nucl. Med. 42:655-661, 2001.
  • Reichert DE and Welch MJ. Applications of Molecular Mechanics to Metal-based Imaging Agents. Coord. Chem. Rev. 212:111-131, 2001.
  • Lewis JS and Welch MJ. PET Imaging of Hypoxia. Quart. J. Nucl. Med. 45:183-188, 2001.
  • Edwards WB, Reichert DE, d'Avignon DA and Welch MJ. β-Cyclodextrin Dimers as Potential Tumor Pretargeting Agents. Chem. Commun., 212(1):1312-1313, 2001.
  • Dearling JLJ, Lewis JS, Mullen GED, Welch MJ, Blower PJ. Copper bis(thiosemicarbazone) complexes as hypoxia imaging agents: structure-activity relationships. Journal of Biological Inorganic Chemistry, 7: 249-259, 2002.
  • Lewis MR, Reichert DE, Laforest R, Margenau WH, Shefer RE, Klinkowstein RE, Hughey BJ and Welch MJ. Production and Purification of Gallium-66 for Preparation of Tumor-targeting Radiopharmaceuticals, submitted for publication. Nucl. Med. Biol. 29:701-706, 2002
  • Lewis JS and Welch MJ. Copper chemistry related to radiopharmaceutical production. In: Technetium, Rhenium and other Metals in Chemistry and Nuclear Medicine 6, Eds: M. Nicolini and U. Mazzi, 23-33, 2002.
  • Vavere A. L., Lewis JS and Welch MJ. Imaging of Antiangiogenic Treatments: Ti-45-transferrin MicroPET as a Surrogate Marker for Tumor Response. In: Technetium, Rhenium and other Metals in Chemistry and Nuclear Medicine 6, Eds: M. Nicolini and U. Mazzi, 101-105, 2002.
  • Edwards WB, Anderson CJ, Fields GB and Welch MJ. Evaluation of Radiolabeled Type IV Collagen Fragments as Potential Tumor Imaging Agents, submitted for publication (Bioconjugate Chem. 12:1057-1065, 2001
  • Lewis JS, Connett JM, Garbow JR, Buettner TL, Fujibayashi Y, Fleshman JW, Welch MJ Copper-64-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for the Prevention of Tumor Growth at Wound Sites following Laparoscopic Surgery: Monitoring Therapy Response with microPET and Magnetic Resonance Imaging. Cancer Research, 62: 445-449, 2002.
  • Dehdashti F, Mintun MA, Lewis JS, Bradley J, Govindan R, Laforest R, Welch MJ, Siegel BA. In Vivo Assessment of Tumor Hypoxia in Lung Cancer with 60Cu-ATSM. Eur J Nucl Med Mol Imaging, 30:844-850, 2003
  • Dehdashti F, Grigsby RW, Mintun MA, Lewis JS, Siegel BA, Welch MJ. Assessing Tumor Hypoxia in Cervical Cancer by Positron Emission Tomography with 60Cu-ATSM: Relationship to Therapeutic Response - A Preliminary Report. International Journal of Radiation Oncology, Biology, and Physics, 55(5):1233-1238, 2003.
  • Aft RL, Lewis JS, Zhang F, Kim J, Welch MJ. Enhancing Targeted Radiotherapy by 64Cu-ATSM using 2-Deoxy-D-Glucose. Cancer Research, 63:5496-5504, 2003.
  • Lewis, M.R., Wang, M., Axworthy, D.B., Theodore, L.J., Mallet, R.W., Fritzberg, A.R., Welch, M.J., Anderson, C.J.: In vivo evaluation of pretargeted copper-64 for tumor imaging and therapy. J. Nucl. Med., (in press)
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Abstracts
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  • Sharma V, Polyakov V, Beatty A, Wey S-P, Bass LA, Dahlheimer J, Crankshaw DL, Green MA, Welch MJ and Piwnica-Worms D. Gallium (III) Schiff-base Complexes as Potential PET Agents for Evaluation of Multidrug Resistance (MDR1) P-Glycoprotein Transport Activity. J. Labelled Cpd. Radiopharm. 42:S723-S725, 1999.
  • Lewis JS, Wang J, Anderson CJ, McCarthy DW and Welch MJ. Comparison of Cell Killing Ability of Copper-64 and Copper-61. J. Labelled Cpd. Radiopharm. 42:S753-S755, 1999.
  • Edwards WB, Reichert DE and Welch MJ. Synthesis and Evaluation of a β-Cyclodextrin Dimer and Bis-t-Butylbenzyl-Cyclen as a New Pretargeting Strategy in Radioimmuno-imaging/Therapy. J. Labelled Cpd. Radiopharm. 42:S838-S840, 1999.
  • Dehdashti F, Mintun MA, Lewis JS, Govindan R and Welch MJ. Evaluation of Tumor Hypoxia with Cu-60 ATSM and PET. J. Nucl. Med. 41(5) 130, 2000.
  • Mathias CJ, Lewis MR, Reichert DE, Laforest R, Sharp TL, Willey LM, Yang ZF, Low PS, Welch MJ and Green MA. Production of the 66Ga for Tumor Imaging Using PET and an Athymic Mouse Model. J. Nucl. Med., 41(5) 164, 2000.
  • Mintun MA, Berger KL, Dehdashti F, Lewis JS, Chao C and Welch MJ. Kinetic Analysis of the Novel Hypoxic Imaging Agent [60Cu]ATSM in Human Neoplasms. J. Nucl. Med. 41(5) 229, 2000.
  • Lewis JS, Sharp TL, Jones LA, Fujibayashi Y, and Welch MJ. Selective 60/64Cu-ATSM Uptake in Hypoxic Tumors Correlated with Direct Tissue Oxygen Measurement, PET Imaging and Electronic Autoradiography. J. Nucl. Med. 41(5) 454, 2000.
  • Lewis MR, Wang M, Jones LA, Axworthy DB, Mallett RW, Fritzberg AR, Welch MJ and Anderson CJ. Radiotherapy and Toxicity of 64Cu Agents for One- and Three-Step Radioimmunotherapy. J. Nucl. Med. 41(5) 565, 2000.
  • Reichert DE, Norrby PO and Welch MJ. Indium and Copper Forcefields Suitable for the Molecular Modelling of Labelled Bi-Functional Chelate Peptide Conjugates. J. Nucl. Med. 41(5) 1083, 2000.
  • Chao C, Bosch W, Mutic S, Cutler PD, Lewis JS, Mintun MA, Dehdashti F, and Welch MJ. An Approach to Hypoxic PET Guided Conformal Radiation Therapy. J. Nucl. Med. 41(5) 1241, 2000.
  • Lewis JS, Buettner TL, Connett JM, Fujibayashi Y and Welch MJ. 64Cu-ATSM as a Radiotherapeutic Agent: Extended Survival in GW39 Tumor-Bearing Hamsters. J. Nucl. Med. 41(5):455, 2000.
  • Vavere AL, Jones LA, McCarthy TJ, Rowland DJ and Welch MJ. Preparation, Biodistribution and microPET Imaging of 45Ti-Transferrin. J. Labelled Cpd. Radiopharm. 44:S793-S795, 2001.
  • McCarthy DW, Bigott HM, Perkins TA, Voller TF and Welch MJ. A Research Resource in Radionuclide Research. J. Labelled Cpd. Radiopharm. 44:S817-S819, 2001.
  • Lewis JS, Connett JM, Garbow JR, Buettner TL, Fujibayashi Y, Fleshman JW and Welch MJ. 64Cu-PTSM as an Inhibitor of Tumor Recurrence. J. Labelled Cpd. Radiopharm. 44:S87-S89, 2001.
  • Bigott HM, McCarthy DW, Wust FR, Dahlheimer JL, Piwnica-Worms DR and Welch MJ. Production, Processing and Uses of 94mTc. J. Labelled Cpd. Radiopharm. 44:S119-S121, 2001.
  • Yoo J, Reichert D and Welch MJ. New N-Substituted Cyclens: Synthesis and Comparative Biodistribution Studies of Cu-64 Complexes. J. Labelled Cpd. Radiopharm. 44:S796-S798, 2001.
  • Lewis JS, Garbow JR, Kim JY, Engelbach JA, Connett JM, Buettner TL, Ye D, Ackerman JJH and Welch MJ. Abstract, High Resolution Imaging in Small Animals Meeting, 2001.
  • Luyt LG, Mull ES, Katzenellenbogen JA, Bigott HM and Welch MJ. Preparation of Cyclopentadienyl Tricarbonyl Technetium-94m Complexes. J. Labelled Cpd. Radiopharm. 44:S489-S490, 2001.
  • Wuest M, Partyka DV, Lewis JS, Motekaitis RM, Martell AE, Welch MJ, Anderson CJ. Synthesis and in vitro evaluation of 64Cu-cyclen-N,N'',N''',N''''-tetrapropionitrile. J Nucl Med. 2000; 41:82P
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